Boronic acid, B-(2-ethoxy-5-Methyl-3-pyridinyl)-
(2-Ethoxy-5-methylpyridin-3-yl)boronic acid
CAS: 1162256-87-2
Molecular Formula: C8H12BNO3
Boronic acid, B-(2-ethoxy-5-Methyl-3-pyridinyl)- - Names and Identifiers
Boronic acid, B-(2-ethoxy-5-Methyl-3-pyridinyl)- - Physico-chemical Properties
| Molecular Formula | C8H12BNO3 |
| Molar Mass | 181 |
| Storage Condition | Sealed in dry,2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD18382896 |
Boronic acid, B-(2-ethoxy-5-Methyl-3-pyridinyl)- - Introduction
boronic acid is an organic compound whose chemical formula is C9H12BNO3. It is a white solid with a melting point of 158-160°C and a molecular weight of 187.01g/mol.
(Br) boronic acid is commonly used as an intermediate in organic synthesis. It can be used as a ligand for metal catalysts and participate in cross-coupling reactions, such as Suzuki coupling reactions and Suzuki-Miyaura coupling reactions, for the construction of carbon-carbon bonds and carbon-heteroatom bonds. In addition, it can also be used for the preparation of bactericides and drug precursors.
(1) The preparation of boronic acid is generally obtained by two-step reaction of ethoxylation and boration. First, 2-ethoxy-5-methylpyridine is reacted with metal lithium to form a metal organic compound, which is then reacted with trialkyl boronic acid to form the final product.
Pay attention to safety precautions when using and storing (boronic acid). It may be irritating to the skin, eyes and respiratory tract, so wear appropriate protective equipment such as gloves, goggles and protective masks during operation. When stored, it should be kept in a dry, cool place, away from fire and oxidizing agents.
(Br) boronic acid is commonly used as an intermediate in organic synthesis. It can be used as a ligand for metal catalysts and participate in cross-coupling reactions, such as Suzuki coupling reactions and Suzuki-Miyaura coupling reactions, for the construction of carbon-carbon bonds and carbon-heteroatom bonds. In addition, it can also be used for the preparation of bactericides and drug precursors.
(1) The preparation of boronic acid is generally obtained by two-step reaction of ethoxylation and boration. First, 2-ethoxy-5-methylpyridine is reacted with metal lithium to form a metal organic compound, which is then reacted with trialkyl boronic acid to form the final product.
Pay attention to safety precautions when using and storing (boronic acid). It may be irritating to the skin, eyes and respiratory tract, so wear appropriate protective equipment such as gloves, goggles and protective masks during operation. When stored, it should be kept in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:01:54
